The monkeypox website makes freely available to the scientific community the first in silico digital archive with more than 30 3D files of virus proteins, pocket mapping data, and molecular dynamics simulations. All models are free to download to accelerate the identification of new drugs.
In May 2022 an atypical outbreak of monkeypox has been declared in the WHO European Region.
The Monkeypox portal’s mission is facilitate information sharing among scientific researchers by providing free access to the first updated and open repository containing 3D models of virus proteins and structural data for Monkeypox’s biological targets. Our purpose is supporting studies to identify new drugs, vaccines, and monoclonal antibodies.
The Monkeypox initiative is a part of the Exscalate4Cov project, an EU initiated consortium making available to the scientific community structural and functional data useful in addressing pathogen caused health crises.
Partners of the project, coordinated by Dompé farmaceutici, are:
note= "A23R Holliday junction resolvase (Cop-A22R) similar to Vaccinia virus strain Copenhagen A22R"
codon_start= 1
product= "MPXVgp133"
protein_id= "URK20571.1"
translation="METSTSSSQSLIPLPMSKKDYSSEIICAFDIGAKNPARTVLEVKDNSVRVLDISKLDWSSDWERRIAQDLSQYEYTTVLLERQPRRSPYVKFIYFIKGFLYHTSAAKVICVSPVMSGNSYRDRKKRSVEAFLDWMDTFGLRDSVPDRRKLDDVADSFNLAMRYVLDKWNTNYTPYNRCKYRNYIKKM"
modelled from 6p7b.1.A template
Seq Identity: 41.67%
Coverage: 24-168
GMQE: 0.57
QMEANDisCo Global: 0.66 ± 0.05
Holliday junction resolvase. Plays a role in DNA replication by cleaving viral DNA concatamers to yield unit-length viral genomes. The concatamer junctions contain inverted repeat sequences that can be extruded as cruciforms, yielding Holliday junctions that A22 protein cleaves.
note= "A6R RNA polymerase subunit (RPO19) (Cop-A5R) precursor of RNA polymerase 22 kDa and 21 kDa similar to Vaccinia virus strain Copenhagen A5R"
codon_start= 1
product= "MPXVgp116"
protein_id= "URK20553.1"
translation="MADTDDIIDYESDDLTEYEDDEEDGESLETSDIDPKSSYKIVESTSTHIEDAHSNLKHIGNHISALKRRYTRRISLFEIAGIIAESYNLLQRGRLPLVSEFSDETMKQNMLHVIIQEIEEGSCPIVIEKNGELLSVNDFDKDGLKFHLDYIIKIWKLQKRY"
modelled from 6rfl.1.C template
Seq Identity: 99.22%
Coverage: 59-161
GMQE: 0.60
QMEANDisCo Global: 0.81 ± 0.08
RPO19, RNA polymerase subunit, 19-kDa subunit. Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
note= "RNA polymerase subunit (RPO132) (Cop-A24R); A25R; similar to Vaccinia virus strain Copenhagen A24R; RNA polymerase, 132 kDa subunit"
codon_start= 1
product= "MPXVgp135"
protein_id= "URG34911.1"
translation="MKKNTDSEMDQRLGYKFLVPDPKAGVFYRPLHFQYVSYSNFILHRLHEILTVKRPLLSFKNNTERIMIEISNVKVTPPDYSPIIASIKGKSYDALATFTVNIFKEVMTKEGISITKISSYEGKDSHLIKIPLLIGYGNKNPLDTAKYLVPNVIGGVFINKQSVEKVGINLVEKITTWPKFRVVKPNSFTFSFSSVSPPNVLPTRYRHYKISLDISQLEASNISSTKTFITVNIVLLSQYLSRVSLEFIRRSLSYDMPPEVVYLVNAIIDSAKRLTESITDFNIDTYINDLVEAEHIKQKSQLTINEFKYEMLHNFLPHMNYTPDQLKGFYMISLLRKFLYCIYHTSRYPDRDSMVCHRILTYGKYFETLAHDELENYIGNIRNDIMNNHKNRGTYAVNIHVLTTPGLNHAFSSLLSGKFKKSDGSYRTHPHYSWMQNISIPRSVGFYPDQVKISKMFSVRKYHPSQYLYFCSSDVPERGPQVGLVSQLSVLSSITNILTSEYLDLEKKICEYIRSYYKDDISYFETGFPITIENALVASLNPNMICDFVTDFRRRKRMGFFGNLEVGITLVRDHMNEIRINIGAGRLVRPFLVVDNGELMMDVCPELESRLDDMTFSDIQKEFPHVIEMVDIEQFTFSNVCESVQKFRMMSKDERKQYDLCDFPAEFRDGYVASSLVGINHNSGPRAILGCAQAKQAISCLSSDIRNKIDNGIHLMYPERPIVISKALETSKIAANCFGQHVTIALMSYKGINQEDGIIIKKQFIQRGGLDIVTAKKHQVEIPLENFNNKERDRSNAYSKLESNGLVRLNAFLESGDAMARNISSRTLEDDFARDNQISFDVSEKYTDMYKSRVERVQVELTDKVKVRVLTMKERRPILGDKFTTRTSQKGTVAYIADETELPYDENGITPDVIINSTSIFSRKTISMLIEVILTAAYSTKPYNNKGENRPVCFPSSNETSIDAYMQFAKQCYEYSNPKLSEEELSDKIFCEKILYDPETDKPYESKVFFGPIYYLRLRHLTQDKATVRCRGKKTKLIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEVLKDSEEDYQDVYICENCGDIAAQIKSINTCLRCSKLNLSPLLTKIDTTHVSKVFLTQMNARGVKVKLDFERRPPSFYKPLDKVDLKPSFLV"
modelled from 6rid.1.B template
Seq Identity: 98.88%
Coverage: 8-1162
GMQE: 0.87
QMEANDisCo Global: 0.88 ± 0.05
RPO132, RNA polymerase subunit, 132-kDa subunit. Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
note= "A35R EEV envelope glycoprotein, needed for formation of actin-containing microvilli and cell-to-cell spread of virion EEV membrane phosphoglycoprotein, C-type lectin-like domain (Cop-A33R) interacts with VAC A36R similar to Vaccinia virus strain Copenhagen A33R"
codon_start= 1
product= "MPXVgp145"
protein_id= "URK20584.1"
translation="MMTPENDEEQTSVFSATVYGDKIQGKNKRKRVIGLCIRISMVISLLSMITMSAFLIVRLNQCMSANKAAITDSAVAVAAASSTHRKVVSSTTQYDHKESCNGLYYQGSCYILHSDYKSFEDAKANCAAESSTLPNKSDVLTTWLIDYVEDTWGSDGNPITKTTSDYQDSDVSQEVRKYFCT"
modelled from 3k7b.2.A template
Seq Identity: 91.01%
Coverage: 96-181
GMQE: 0.36
QMEANDisCo Global: 0.78 ± 0.09
EEV envelope phosphoglycoprotein, needed for formation of actin-containing microvilli and cell-to-cell spread of virion EEV, C-type lectin-like domain interacts with VAC A36R
note= "A49R Thymidylate kinase (Cop-A48R) similar to Vaccinia virus strain Copenhagen A48R thymidylate kinase"
codon_start= 1
product= "MPXVgp159"
protein_id= "URK20597.1"
translation="MSRGALIVFEGLDKSGKTTQCMNIMESIPANTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYATAKGASMTLSKSYESGLPKPDLVIFLESGSKEINRNIGEEIYEDVEFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAIHTVTGPVGQLWM"
modelled from 2v54.1.A template
Seq Identity: 98.53%
Coverage: 1-204
GMQE: 0.97
QMEANDisCo Global: 0.93 ± 0.05
Thymidylate kinase, able to phosphorylate dTMP, dUMP and also dGMP from any purine and pyrimidine nucleoside triphosphate.
note= "B3R Ser/Thr Kinase (Cop-B1R) serine similar to Vaccinia virus strain Copenhagen B1R"
codon_start= 1
product= "MPXVgp164"
protein_id= "URK20602.1"
translation="MKFQGLVLIDNCKNQWVVGPLIGKGGFGSIYTTNDNNYVVKIEPKANGSLFTEQAFYTRVLKPSVIEEWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGADLDAVIRANNNRLPERSVMLIGIEILNTIQFMHEQGYSHGDIKASNIVLDQIDKNKLYLVDYGLVSKFMSNGEHVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKNSALVSAAKQKYVNNTATLLMTSLQYAPRELLQYITMVNSLTYFEEPNYDEFRRVLMNGVMKNFC"
modelled from 5ukf.1.A template
Seq Identity: 39.02%
Coverage: 10-298
GMQE: 0.73
QMEANDisCo Global: 0.70 ± 0.05
B3R Ser/Thr Kinase (Cop-B1R) serine similar to Vaccinia virus strain Copenhagen B1R.
note= "B9R similar to Vaccinia virus strain Copenhagen B8R Soluble IFN-g receptor-like protein (Cop-B8R) secretedIFN-g binding protein"
codon_start= 1
product= "MPXVgp170"
protein_id= "URK20608.1"
translation="MRYIIILAVLFINSIHAKITSYKFESVNFDSKIEWTGDGLYNISLKNYGIKTWQTMYTNVPEGTYDISGFPKNDFVSFWVKFEQGDYKVEEYCTGLCVEVKIGPPTVILTEYDDHINLFIEHPYATRGSKKIPIYKRGDMCDIYLLYTANFTFGDSEEPVTYDIDDYDCTSTGCSIDFATTEKVCVTAQGATEGFLEKITPWSSEVCLTPKKNVYTCAIRSKEDVPNFKDKIARVITRKFNKQSQSYLTKFLGSTSNDVTTFFSILD"
modelled from 3bes.1.B template
Seq Identity: 91.57%
Coverage: 19-267
GMQE: 0.88
QMEANDisCo Global: 0.91 ± 0.05
IFN-γ binding protein, receptor /secreted.
note= "B16R IFN-alpha/beta receptor glycoprotein (Cop-B19R) cell surface antigen and secreted IFN-a similar to Vaccinia virus strain Copenhagen B19R"
codon_start= 1
product= "MPXVgp177"
protein_id= "URK20616.1"
translation="MKMKMMVRIYFVSLSLLLFHSYAIDIENEITEFFNKMRDTLPAKDSKWLNPVCMFGGTMNDMAALGEPFSAKCPPIEDSLLSHRYKDYVVKWERLEKNRRRQVSNKRVKHGDLWIANYTSKFSNRRYLCTVTTKNGDCVQGVVRSHVWKPSSCIPKTYELGTYDKYGIDLYCGILYANHYNNITWYKDNKEINIDDFKYSQAGKELIIHNPELEDSGRYDCYVHYDDVRIKNDIVVSRCKILTVIPSQDHRFKLILDPKINVTIGEPANITCSAVSTSLFVDDVLIEWENPSGWIIGLDFGVYSILTSRGGITEATLYFENVTEEYIGNTYTCRGHNYYFDKTLTTTVVLE"
modelled from 3oq3.1.B template
Seq Identity: 89.57%
Coverage: 24-351
GMQE: 0.89
QMEANDisCo Global: 0.87 ± 0.05
IFN-a/β binding glycoprotein/ secreted.
note= "CC-chemokine binding Chemokine binding protein (Cop-C23L) J3R similar to Vaccinia virus strain Copenhagen B29R"
codon_start= 1
product= "MPXVgp191"
protein_id= "URK20629.1"
translation="MKQYIVLACMCLVAAAMPTSLQQSSSSCTEEENKHHMGIDVIIKVTKQDQTPTNDKICQSVTEVTETEDDEVSEEVVKGDPTTYYTIVGAGLNMNFGFTKCPKILSISESSDGNTVNTRLSSVSPGQGKDSPAITREEALAMIKDCEMSIDIRCSEEEKDSDIKTHPVLGSNISHKKVSYKDIIGSTIVDTKCVKNLEFSVRIGDMCEESSELEVKDGFKYVDGSASEGATDDTSLIDSTKLKACV"
modelled from 1cq3.1.A template
Seq Identity: 87.95%
Coverage: 19-246
GMQE: 0.81
QMEANDisCo Global: 0.84 ± 0.05
CC-chemokine binding Chemokine binding protein (vCKBP). Inhibits host immune defense by binding to host chemokines. Binds host CC chemokines (beta chemokines) such as RANTES with high affinity, but not CXC or C chemokines (alpha and gamma chemokines).
note= "J2L TNF receptor (CrmB) (Cop-C22L)"
codon_start= 1
product= "MPXVgp002"
protein_id= "URK20441.1"
translation="MRSVLYSYILFLSCIIINGRDIAPHAPSNGKCKDNEYRSRNLCCLSCPPGTYAFRLCDSKTNTQCTPCGSDTFTSHNNHLQACLSCNGRCDSNQVETRSCNTTHNRICECSPGYYCLLKGASGCRTCISKTKCGIGYGVSGYTSTGDVICSPCGPGTYSHTVSSTDKCEPVVTSNTFNYIDVEINLYPVNDTSCTRTTTTGLSESISTSELTITMNHKDCDPVFRAEYFSVLNNVATSGFFTGENRYQNTSKICTLNFEIKCNNKDSSSKQLTKTKNDTIMPHSETVTLVGDCLSSVDIYILYSNTNTQDYENDTISYHMGNVLDVNSHMPASCDIHKLITNSQNPTHL"
modelled from 3on9.1.A template
Seq Identity: 51.57%
Coverage: 176-337
GMQE: 0.36
QMEANDisCo Global: 0.76 ± 0.07
Secreted TNF-binding protein or cytokine response modifier B (CrmB).
note= "E1R RNA 5' triphosphatase and RNA guanylyl transferase activities mRNA capping enzyme large subunit (Cop-D1R) mRNA capping enzyme, large subunit similar to Vaccinia virus strain Copenhagen D1R"
codon_start= 1
product= "MPXVgp098"
protein_id= "URK20535.1"
translation="MDANIVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGIKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNETVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSKGLYCYFTHLGYIIRYPVKRTIDSEVVVFGEAVKDKNWTVYLIKLIEPVNAISDRLEESKYVESKLVDICDRIVFKSKKYEGPFTTTSEVVDMLSTYLPKQPEGVILFYSKGPKSNIDFKIKKENTIDQTANVVFRYMSSEPIIFGESSIFIEYKKFTNDKGFPKEYGSGKIVLYNGVNYLNNIYCLEYINTHNEVGIKSVVVPIKFIAEFLVNGEILKPRIDKTMKYINSEDYYGNQHNIIVEHLRDQSIKIGDVFNEDKLSDVGHQYAANNDKFRLNPEVSYFTNKRTRGPLGILSNYVKTLLISMYCSKTFLDDSNKRKVLAIDFGNGADLEKYFYGEIALLVATDPDADAIARGNERYNKLNSGIKTKYYKFDYIQETIRSDTFVSSVREVFYFGKFNIIDWQFAIHYSFHPRHYATVMNNLSELTASGGKVLITTMDGDKLSKLTDKKTFIIHKNLPSSENYMSVEKIADDRIVVYNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERSKKFINGASTMEDRPSTRNFFELNRGAIKCEGLDVEDLLSYYVVYVFSKR"
modelled from 6rfl.1.H template
Seq Identity: 98.82%
Coverage: 8-845
GMQE: 0.91
QMEANDisCo Global: 0.88 ± 0.05
RNA 5' triphosphatase and RNA guanylyltransferase activities mRNA capping enzyme large subunit.
note= "E4R Uracil-DNA glycosylase, DNA polymerase processivity factor (Cop-D4R) similar to Vaccinia virus strain Copenhagen D4R uracil DNA glycosylase"
codon_start= 1
product= "MPXVgp101"
protein_id= "URK20538.1"
translation="MNSVTISHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDHQFEKDRSFEIINVLLELDNKTPINWAQGFIY"
modelled from 4lzb.2.A template
Seq Identity: 98.17%
Coverage: 1-218
GMQE: 0.96
QMEANDisCo Global: 0.89 ± 0.05
Uracil-DNA glycosylase.
note= "E7R RNA polymerase subunit (RPO18) (Cop-D7R) RNA polymerase, 18 kDa subunit similar to Vaccinia virus strain Copenhagen D7R"
codon_start= 1
product= "MPXVgp104"
protein_id= "URK20541.1"
translation="MNSVTISHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDHQFEKDRSFEIINVLLELDNKTPINWAQGFIYMSSFVTNGYLPVTLEPHELTLDIKTNIRNAVYKAYLHREISGKMAKKIEIREDVELPLGEIVNNSVVINVPCVITYAYYHVGDIVRGTLNIEDESNVTIQCGDLICKLSRDSGTVSFSDSKYCFFRNGNAYDNGIEVSAVLMEAQQGTESSFVFLANIVDS"
modelled from 7amv.1.F template
Seq Identity: 96.89%
Coverage: 2-159
GMQE: 0.91
QMEANDisCo Global: 0.86 ± 0.07
RPO18, RNA pol 18-kDa subunit.
note= "Carbonic anhydrase, GAG-binding IMV membrane protein (Cop-D8L) E8L IMV adsorption to cell surface IMV surface membrane 32 kDa protein binding to cell surface chondroitin sulfate similar to Vaccinia virus strain Copenhagen D8L"
codon_start= 1
product= "MPXVgp105"
protein_id= "URK20542.1"
translation="MPQQLSPINIETKKAISDARLKTLDIHYNESKPTTIQNTGKLVRINFKGGYISGGFLPNEYVLSTIHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGIIIIAIFLQVSDHKNVYFQKIVNQLDSIRSANMSAPFDSVFYLDNLLPSTLDYFTYLGTTINHSADAAWIIFPTPINIHSDQLSKFRTLLSSSNHEGKPHYITENYRNPYKLNDDTQVYYSGEIIRAATTSPVRENYFMKWLSDLREACFSYYQKYIEGNKTFAIIAIVFVFILTAILFLMSQRYSREKQN"
modelled from 4e9o.1.A template
Seq Identity: 94.25%
Coverage: 2-234
GMQE: 94.25%
QMEANDisCo Global: 94.25%
Carbonic anhydrase, GAG-binding IMV surface membrane protein, IMV adsorption to cell surface chondroitin sulfate.
note= "ATPase, NPH1 (Cop-D11L) DNA-dependent ATPase E11L early gene transcription termination factor nucleoside triphosphate phosphohydrolase I, NPH I similar to Vaccinia virus strain Copenhagen D11L"
codon_start= 1
product= "MPXVgp108"
protein_id= "URK20545.1"
translation="MSKSHAAYIDYALRRTTNMPVEMMGSDVVRLKDYQHFVARVFLGLDSMHSLLLFHETGVGKTMTTVYILKHLKDIYTNWAIILLVKKALIEDPWINTILRYAPEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLIKEDGKIRPTRSVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLRPGSLQHQSLFENKRLVDEKELVSKLGGLCSYIVNNEFSIFDDVEGSASFAKKTVLMRYVNMSKKQEEIYQKAKLAEIKTGISSFRILRRMATTFTFDSFPERQNRDPGEYAQEIATLYNDFKNSLRDREFSKSALDTFKKGELLGGDAIAADISLFTELKEKSVKFIDVCLGILASHGKCLVFEPFVNQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEFNQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGRAIRLNSHVLTPPERRYVNVHFIMARLSNGMPTVDEDLFEIIQNKSKEFVQLFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDLSSKKNITNKLIEGTNIWYSNSNRLISINRGFKGVDGRVYDVDGNYLHDMPDNPVIKIHDGKLIYIF"
modelled from 6rfl.1.N template
Seq Identity: 99.21%
Coverage:3-631
GMQE: 0.89
QMEANDisCo Global: 0.85 ± 0.05
ATPase, NPH1 (Cop-D11L) DNA-dependent ATPase E11L early gene transcription termination factor nucleoside triphosphate phosphohydrolase I, NPH I similar to Vaccinia virus strain Copenhagen D11L.
note= "E12Lsimilar to Vaccinia virus strain CopenhagenD12L mRNA capping enzyme small subunit (Cop-D12L)mRNA(guanine-N7-)-methyl-transferase mRNAcapping enzyme,small subunit transcription initiationfactor"
codon_start= 1
product= "MPXVgp109"
protein_id= "URK20546.1"
translation="MDEIVKNIREGTHVLLPFYETLPELNLSLGKSPLPSLEYGANYFLQISRVNDLNRMPTDMLKLFTHDIMLPESDLDKVYEILKINSVKYYGRSTRADAVVADLSARNKLFKRERDAIKSNNHLTENNLYISDYKMLTFDVFRPLFDFVNEKYCIIKLPTLFGRGVIDTMRIYCSLFKNVRLLKCVSDSWLKDSAIMVASDVYKKNLDLFMSHVKSVTKSSSWKDVNTVQFSILNDPVDTEFINKFLEFSNRVYEALYYVHSLLYSSMTSDSKSIENKHQRRLVKLLL"
modelled from 4ckb.1.B template
Seq Identity: 98.61%
Coverage: 1-287
GMQE: 0.90
QMEANDisCo Global: 0.84 ± 0.05
mRNA capping enzyme small subunit transcription initiation factor, (guanine-N7-)-methyl-transferase mRNA capping enzyme.
note= "Trimeric virion coat protein (rifampicin res) (Cop-D13L); E13L; similar to Vaccinia virus strain Copenhagen D13L; protein needed for the formation of immature IMV surface membrane"
codon_start= 1
product= "MPXVgp110"
protein_id= "URG34885.1"
translation="MNNTIINSLIGGDDFIKRSNVFAVDSQIPTLYMPQYISLSGVMTNDGPDNQAIASFEIRDQYITALNHLVLSLELPEVKGMGRFGYVPYVGYKCINHVSVSSCNGVIWEIEGEELYNNCINNTIALKHSGYSSELNDISIGLTPNDTIKEPSTVYVYIKTPFDVEDTFSSLKLSDSKITVTVTFNPVSDIVIRDSSFDFETFNKEFVYVPELSFIGYMVKNVQIKPSFIEKPRRVIGQINQPTATVTEVHAATSLSVYTKPYYGNTDNKFISYPGYSQDEKDYIDAYVSRLLDDLVIVSDGPPTGYPESAEIVEVPEDGVVSIQDADVYVKIDNVPDNMSVYLHTNLLMFGTRKNSFIYNISKKFSAITGTYSDATKRTVFAHISHTINIIDTSIPVSLWTSQRNVYNGDNRSAESKAKDLFINDPFIKGIDFKNKTDIISRLEVRFGNDVLYSENGPISRIYNELLTKSNNGTRTLTFNFTPKIFFRPTTITANVSRGKDKLSVRVVYSTMDINHPIYYVQKQLVVVCNDLYKVSYDQGVSITKIMGDNN"
modelled from 6beb.1.A template
Seq Identity: 98.73%
Coverage: 1-547
GMQE: 0.94
QMEANDisCo Global: 0.92 ± 0.05
Trimeric virion coat scaffold protein (rifampicin resistant), protein needed for the formation of immature IMV surface membrane
note= "F1L Poly (A) polymerase catalytic subunit (VP55) (Cop-E1L) poly-A polymerase, catalytic subunit similar to Vaccinia virus strain Copenhagen E1L"
codon_start= 1
product= "MPXVgp050"
protein_id= "URK20486.1"
translation="MNRNPDQNTLPNITLKIIETYLGRVPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFFFDVDTSASEIKDRILSYFSKQTQTYNIGKLFTIIELQSVLVTTYTDILGVLTIKAPNVISSKISYNVTSMEELARDMLNSMNVAVIDKAKVMGRHNVSSLVKNVNKLMEEYLRRHNKSCICYGSYSLYLINPNIRYGDIDILQTNSRTFLIDLAFLIKFITGNNIILSKIPYLRNYMVIKDENDNHIIDSFNIRQDTMNIVPKIFIDNIYIVDPTFQLLNMIKMFSQIDRLEDLSKDPEKFNVRMATMLEYVRYTHGIVFDGTRNNMPMKCIIDENNRIVTVTTKDYFSFKKCLVYLDENVLSSDILDLNADTSCDFESVTNSVYLIHDNIMYTYFSNTILLSDKGKVHEISARGLCAHILLYQMLTSGEYKQCLSDLLNSMMNRDKIPIYSHTERDKKPGRHGFINIEKDIIVF"
modelled from 3er9.1.B template
Seq Identity: 98.75%
Coverage: 12-479
GMQE: 0.90
QMEANDisCo Global: 0.88 ± 0.05
Poly(A) polymerase catalytic subunit (VP55)
note= "DNA polymerase (Cop-E9L) DNA polymerase, catalytic subunit F8L similar to Vaccinia virus strain Copenhagen E9L"
codon_start= 1
product= "MPXVgp057"
protein_id= "URK20494.1"
translation="MDVRCINWFESHGENRFLYLKSRCRNGETVFIRFPHYFYYVVTDEIYQSLSPPPFNARPMGKMRTIDIDETISYNLDIKDRKCSVADMWLIEEPKKRSIQNATMDEFFNISWFYISNGISPDGCYSLDEQYLTKINNGCYHCDDPRNCFAKEIPRFDIPRSYLFLDIECHFDKKFPSVFINPISHTSYCYIDLSGKRLLFTLINEEMLTEQEIQEAVDRGCLRIQSLMEMDYERELVLCSEIVLLRIAKQLLELTFDYVVTFNGHNFDLRYITNRLELLTGEKIIFRSPDKKEAVHLCIYERNQSSHKGVCGMANTTFHVNNNNGTIFFDLYSFIQKSEKLDSYKLDSISKNAFSCMGKVLNRGVREMTFIGDDTTDAKGKADTFAKVLTTGNYVTVDEDIICKVIRKDILENGFKVVLSCPTLPNDIYKLSFGKDDIDLAQMYKDYNLNIALDMARYCIHDACLCQYLWEYYGVETKTDAGAATYVLPQSMVFEYRASTIIKGPLLKLLLETKTILVRSETKQKFPYEGGKVFAPKQKMFSNNVLIFDYNSLYPNVCIFGNLSPETLVGVVVSTNRLEEEINNQLLLQKYPPPRYITVHCEPRLPNLISEIAIFDRSIEGTIPRLLRTFLAERARYKKMLKQATSSTEKAIYDSMQYTYKIVANSVYGLMGFRNSALYSYASAKSCTSIGRRMILYLESVLNGAELSNGMLRFANTLSNPFYMDDRDINPIVKTSLPIDYRFRFRSVYGDTDSVFTEIDSQDVDKSIEIAKELERLINSRVLFNNFKIEFEAVYKNLIMQSKKKYTTMKYSASSNSKSVPERINKGTSETRRDVSKFHKNMIKTYKTRLSEMLSEGRMNSNQVCIDILRSLETDLRSEFDSRSSPLELFMLSRMHHSNYKSADNPNMYLVTEYNKNNPETIELGERYYFAYICPANVPWTKKLVNIKTYETIIDRSFKLGSNQRIFYEVYFKRLTSEIVNLLDNKVLCISFFQRMFGSRPTFYEA"
modelled from 5n2e.1.A template
Seq Identity: 98.31%
Coverage: 2-1005
GMQE: 0.92
QMEANDisCo Global: 0.93 ± 0.05
DNA polymerase, catalytic subunit.
note= "F4L RNA polymerase 30 kDa subunit RNA polymerase subunit (RPO30) (Cop-E4L) similar to Vaccinia virus strain Copenhagen E4L simultaneously intermediate stage promoter-specific transcription factor, VITF-1"
codon_start= 1
product= "MPXVgp053"
protein_id= "URK20489.1"
translation="MDVRCINWFESHGENRFLYLKSRCRNGETVFIRFPHYFYYVVTDEIYQSLSPPPFNARPMGKMRTIDIDETISYNLDIKDRKCSVADMWLIEEPKKRSIQNATMDEFFNISWFYISNGISPDGCYSLDEQYLTKINNGCYHCDDPRNCFAKEIPRFDIPRSYLFLDIECHFDKKFPSVFINPISHTSYCYIDLSGKRLLFTLINEEMLTEQEIQEAVDRGCLRIQSLMEMDYERELVLCSEIVLLRIAKQLLELTFDYVVTFNGHNFDLRYITNRLELLTGEKIIFRSPDKKEAVHLCIYERNQSSHKGVCGMANTTFHVNNNNGTIFFDLYSFIQKSEKLDSYKLDSISKNAFSCMGKVLNRGVREMTFIGDDTTDAKGKADTFAKVLTTGNYVTVDEDIICKVIRKDILENGFKVVLSCPTLPNDIYKLSFGKDDIDLAQMYKDYNLNIALDMARYCIHDACLCQYLWEYYGVETKTDAGAATYVLPQSMVFEYRASTIIKGPLLKLLLETKTILVRSETKQKFPYEGGKVFAPKQKMFSNNVLIFDYNSLYPNVCIFGNLSPETLVGVVVSTNRLEEEINNQLLLQKYPPPRYITVHCEPRLPNLISEIAIFDRSIEGTIPRLLRTFLAERARYKKMLKQATSSTEKAIYDSMQYTYKIVANSVYGLMGFRNSALYSYASAKSCTSIGRRMILYLESVLNGAELSNGMLRFANTLSNPFYMDDRDINPIVKTSLPIDYRFRFRSVYGDTDSVFTEIDSQDVDKSIEIAKELERLINSRVLFNNFKIEFEAVYKNLIMQSKKKYTTMKYSASSNSKSVPERINKGTSETRRDVSKFHKNMIKTYKTRLSEMLSEGRMNSNQVCIDILRSLETDLRSEFDSRSSPLELFMLSRMHHSNYKSADNPNMYLVTEYNKNNPETIELGERYYFAYICPANVPWTKKLVNIKTYETIIDRSFKLGSNQRIFYEVYFKRLTSEIVNLLDNKVLCISFFQRMFGSRPTFYEA"
modelled from 7aoh.1.K template
Seq Identity: 97.68%
Coverage: 23-151
GMQE: 0.44
QMEANDisCo Global: 0.65 ± 0.07
RPO30, RNA polymerase subunit/ 30-kDa subunit.
note= "C10L Ribonucleotide reductase small subunit (Cop-F4L) ribonucleotide reductase, small subunit, R2 similar to Vaccinia virus strain Copenhagen F4L"
codon_start= 1
product= "MPXVgp036"
protein_id= "URK20471.1"
translation="MEPILAPNPNRFVIFPIQYHDIWNMYKKAEASFWTVEEVDISKDINDWNKLTPDEKYFIKHVLAFFAASDGIVNENLAERFCTEVQITEARCFYGFQMAIENIHSEMYSLLIDTYVKDSNEKNYLFNAIETMPCVKKKADWAQKWIHDSAGYGERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLLHPPSEETVRFIITNAVSIEQEFLTVALPVKLIGMNCEMMKTYIEFVADRLISELGFKKIYNVTNPFDFMENISLEGKTNFFEKRVGEYQKMGVMSQEDNHFSLDVDF"
modelled from 3olj.1.A template
Seq Identity: 81.79%
Coverage: 2-281
GMQE: 0.83
QMEANDisCo Global: 0.86 ± 0.05
Ribonucleoside-diphosphate reductase, small subunit/ holoenzyme provides the precursors necessary for viral DNA synthesis.
note= "C15L S-S bond formation pathway protein substrate (Cop-F9L) similar to Vaccinia virus strain Copenhagen F9L"
codon_start= 1
product= "MPXVgp041"
protein_id= "URK20476.1"
translation="MAETKEFKTLYNLFIDSYLQKLAQHSIPTNVTCAIHIGEVIGQFKNCALRITNKCMSNSRLSFTLMVESFIEVISLLSEKDRRAIAEEIGIDLDDVPSVVSKLEKNCNAYAEVNNIIDIQKLNIGECSAPPGQHMLLQIVNTGSAEANCGLQTIVKSLNKIYVPPIIENRLPYYDPWFLVGVAIILVIFTVAICSIRRNLALKYRYGTFLYV"
modelled from 6cj6.1.A template
Seq Identity: 98.30%
Coverage: 2-166
GMQE: 0.73
QMEANDisCo Global: 0.87 ± 0.07
Membrane protein (MV), S-S bond formation pathway protein substrate.
note= "H1L Tyr/Ser phosphatase, IFN-gamma inhibitor (Cop-H1L) similar to Vaccinia virus strain Copenhagen H1Ltyrosine"
codon_start= 1
product= "MPXVgp091"
protein_id= "URK20528.1"
translation="MDKKSLYKYLLLRSTGDMHRAKSPTIMTRVTNNVYLGNYKNAMDAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHCVAGVNRSGAMILAYLMSKNKESSPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYVIDKN"
modelled from 2rf6.1.A template
Seq Identity: 97.66%
Coverage: 1-168
GMQE: 0.94
QMEANDisCo Global: 0.91 ± 0.05
Serine/tyrosine phosphatase, IFN signaling evasion.
note= "H3L similar to Vaccinia virus strain Copenhagen H3LIMV heparin binding surface protein (Cop-H3L) IMVsurfacemembrane protein"
codon_start= 1
product= "MPXVgp093"
protein_id= "URK20530.1"
translation="MAAVKTPVIVVPVIDRPPSETFPNVHEHINDQKFDDVKDNEVMQEKRDVVIVNDDPDHYKDYVFIQWTGGNIRDDDKYTHFFSGFCNTMCTEETKRNIARHLALWDSKFFTELENKNVEYVVIIENDNVIEDITFLRPVLKAIHDKKIDILQMREIITGNKVKTELVIDKDHAIFTYTGGYDVSLSAYIIRVTTALNIVDEIIKSGGLSSGFYFEIARIENEMKINRQIMDNSAKYVEHDPRLVAEHRFETMKPNFWSRIGTVAAKRYPGVMYTFTTPLISFFGLFDINVIGLIVILFIMFMLIFNVKSKLLWFLTGTFVTAFI"
modelled from 5ej0.1.A template
Seq Identity: 93.25%
Coverage: 4-240
GMQE: 0.59
QMEANDisCo Global: 0.81 ± 0.05
Immunodominant envelope protein (IMV), Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell.
note= "I4L Ribonucleotide reductase large subunit (Cop-I4L) ribonucleotide reductase, large subunit, R1 similar to Vaccinia virus strain Copenhagen I4L"
codon_start= 1
product= "MPXVgp065"
protein_id= "URK20502.1"
translation="MFVIKRNGYKENVMFDKITSRIRKLCYGLNTDHIDPIKIAMKVIQGIYNGVTTVELDTLAAEIAATCTTQHPDYAILAARIAISNLHKETKKLFSEVMEDLFNYVNPKNGKHSPIISSITMDIVNKYKDKLNSVIIYERDFSYNYFGFKTLEKSYLLKINNKIVERPQHMLMRVAVGIHQWDIDSAIETYNLLSEKWFTHASPTLFNAGTTRHQMSSCFLLNMIDDSIEGIYDTLKRCALISKMAGGIGLSISNIRASGSYISGTNGISNGIIPMLRVYNNTARYIDQGGNKRPGVMAIYLEPWHSDIMAFLDLKKNTGNDEHRTRDLFIALWIPDLFMKRVKDDGEWSLMCPDECPGLDNVWGDEFERLYTLYERERRYKCIIKARVVWKAIIESQIETGTPFILYKDACNKKSNQQNLGTIKCSNLCTEIIQYADANEVAVCNLASVALNMFVIDGRFDFLKLKDVVKVIVRNLNKIIDINYYPIPEAEISNKRHRPIGIGVQGLADAFILLNYPFDSLEAQDLNKKIFETIYYGALEASCKLAEKEGPYDTYVGSYASNGILQYDLWNVVPSDLWNWEPLKDKIRTYGLRNSLLVAPMPTASTAQILGNNESVEPYTSNIYTRRVLSGEFQVVNPHLLRVLTERKLWNDEIKNRIMVDGGSIQNTNLPEDIKRVYKTIWEIPQKTIIKMAADRGAFIDQSQSMNIHIADPSYSKLTSMHFYGWSLGLKTGMYYLRTKPASAPIQFTLDKDKIKPQVVCDSEICTSCSG"
modelled from 3hnc.1.A template
Seq Identity: 75.63%
Coverage: 14-740
GMQE: 0.84
QMEANDisCo Global: 0.82 ± 0.05
RAP94, RNA-polymerase associated protein/ Ribonucleotide reductase large subunit.
note= "L2R Thymidine kinase (Cop-J2R) similar to Vacciniavirus strain Copenhagen J2R thymidine kinase"
codon_start= 1
product= "MPXVgp086"
protein_id= "URK20523.1"
translation="MNGGHIQLIIGPMFSGKSTELIRRVRRYQIAQYKCVTIKYSNDNRYGTGLWTHDKNNFAALEVTKLCDVLEAITDFSVIGIDEGQFFPDIVEFCERMANEGKIVIVAALDGTFQRRPFNNILNLIPLSEMVVKLTAVCMKCFKEASFSKRLGTETEIEIIGGNDMYQSVCRKCYIDS"
modelled from 1w4r.1.A template
Seq Identity: 67.43%
Coverage: 3-176
GMQE: 0.86
QMEANDisCo Global: 0.81 ± 0.05
Thymidine kinase (TK).
note= "L4R RNA polymerase subunit (RPO22) (Cop-J4R) RNA polymerase, 22 kDa subunit similar to Vaccinia virus strain Copenhagen J4R"
codon_start= 1
product= "MPXVgp088"
protein_id= "URK20525.1"
translation="MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVFNESSINYTPVDDDYGEPIIITSYLQKGHNKFPVNFLYIDVVISDLFPSFVRLDTTETNIVNSVLQTGDGKKTLRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISVAD"
modelled from 7amv.1.D template
Seq Identity: 100.00%
Coverage: 1-184
GMQE: 0.90
QMEANDisCo Global: 0.84 ± 0.06
Rpo22, RNA polymerase subunit/22-kDa subunit.
note= "L6R RNA polymerase subunit (RPO147) (Cop-J6R) RNA polymerase, 147 kDa subunit similar to Vaccinia virus strain Copenhagen J6R"
codon_start= 1
product= "MPXVgp090"
protein_id= "URK20527.1"
translation="MAVISKVTYSLYDQKEINATDIIISHIKNDDDIGTVKDGRLGAMDGALCKTCGKTELECFGHWGKVSIYKTHIVKPEFISEIIRLLNHICIHCGLLRSREPYSDDINLKELSVHALRRLKDKILSKKKSCWNSECMQPYQKITFSKKKVCFVNKLDDINVPNSLIYQKLISIHEKFWPLLEIHQYPANLFYTDYFPIPPLIIRPAISFWIDSIPKETNELTYLLGMIVKNCNLNADEQVIQKAVIEYDDIKIISNNTTSINLSYITSGKNNMIRSYIVARRKDQTARSVIGPSTSITVNEVGMPTYIRNTLTEKIFVNAFTVDKVKQLLASNQVKFYFNKRLNQLTRIRQGKFIKNKIHLLPGDWVEVAVQEYTSIIFGRQPSLHRYNVIASSIRATEGDTIKISPGIANSQNADFDGDEEWMILEQNPKAVVEQSILMYPTTLLKHDIHGAPVYGSIQDEIVAAYSLFRIQDLCLDEVLNILGKYGREFDPKGKCKFSGKDIYTYLIGEKINYPGLLKDGEIIANDVDSNFVVAMRHLSLAGLLSDHKSNVEGINFIIKSSYVFKRYLSIYGFGVTFKDLRPNSTFTNKLEAINVEKIELIKEAYAKYLKDVRDGKIVPLSKALEADYLESMLSNLTNLNIREIEEHMRQTLIDDPDNNLLKMAKAGYKVNPTELMYILGTYGQQRIDGEPAETRVLGRVLPYYLPDSKDPEGRGYILNSLTKGLTGSQYYFLMLVARSQSTDIVCETSRTGTLARKIIKKMEDMVVDGYGQVVIGNTLIKYAANYTKILGSVCKPVDLIYPDESMTWYLEISALWNKIKQGFVYSQKQKLAKKTLAPFNFLVFVKPTTEDNAIKVKDLYDMIHNVIDDVREKYFFTVSNIDFMEYIFLTHLNPSRIRITKETAITIFEKFYEKLNYTLGGGTPIGIISAQVLSEKFTQQALSSFHTTEKSGAVKQKLGFNEFNNLTNLSKNKTEIITLVSDDISKLQSVKINFEFVCLGELNPDITLRKETDRYVVDIIVNRLYIKRAEITELVVEYMIERFISFSVIVKEWGMETFIEDEDNIRFTIYLNFVEPEELNLSKFMMVLPGAANKGKISKFKIPISDYTGYNDFNQTKKLNKMTVELMNLKELGSFDLENVNVYPGVWNTYDIFGIEAARGYLCEAMLNTYGEGFDYLYQPCDLLASLLCASYEPESVNKFKFGAASTLKRATFGDNKALLNAALHKKSEPINDNSSCHFFSKVPNIGTGYYKYFIDLGLLMRMERKLSDKISSQKIKEIEETEDF"
modelled from 6ric.1.A template
Seq Identity: 98.99%
Coverage: 2-1267
GMQE: 0.84
QMEANDisCo Global: 0.87 ± 0.05
Rpo147, RNA polymerase subunit/147-kDa subunit.
note= "IMV membrane protein (Cop-L1R) M1R myristylated IMV surface membrane protein similar to Vaccinia virus strain Copenhagen L1R"
codon_start= 1
product= "MPXVgp080"
protein_id= "URK20517.1"
translation="MGAAASIQTTVNTLSERISSKLEQEANASAQTKCDIEIGNFYIRQNHGCNITVKNMCSADADAQLDAVLSAATETYSGLTPEQKAYVPAMFTAALNIQTSVNTVVRDFENYVKQTCNSSAVVDNKLKIQNVIIDECYGAPGSPTNLEFINTGSSKGNCAIKALMQLTTKATTQIAPRQVAGTGVQFYMIVIGVIILAALFMYYAKRMLFTSTNDKIKLILANKENVHWTTYMDTFFRTSPMIIATTDIQN"
modelled from template
Seq Identity: 98.91%
Coverage: 4-185
GMQE: 0.65
QMEANDisCo Global: 0.65
Structural protein with role in virion assembly / Myristylated 25-kDa surface membrane protein (IMV).
note= "P4c precursor (Cop-A26L); A28L; major component of IMV surface tubules; p4c"
codon_start= 1
product= "MPXVgp138"
protein_id= "URG34914.1"
translation="MANIINLWNGIVPMVQDVNVASITAFKSMIDETWDKKIEANTCISRKHRNIIHEVIRDFMKAYPKMDENRKSPLGAPMQWLTQYYILKNEYHKTMLAYDDGSLNTKFKTLNIYMITNVGQYILYIVFCIISGKNHDGTPYIYDSEITSNDKNLINDRIKYACKQILHGQLTMALRIRNKFMFIGSPMYLWFNVNGSHVYHEIYDRNVGFHNKEIGRLLYAFMYYLSISGRFLNDLALLKFTYLGESWTFSLSVPEYILYGLGYSVFDTIEKFSNDAILVYIRTNNRNGYDYAEFNKKGIVKVTEDKPDNDKRIHAIRLINYSSDVQHIHFGFRNTLIIDNECTNIQSSAENATDIGHYQDSKINIEDDDIIDDDDDDDDDDDDDDYNPKPTPIPDPHPRPPFPRHDYHKRPKLLPVEEPDPVKKDADRIRLDNHILNTLDHNLNSIGHYCCDTVAVDRLEHHIETLGQYTVILARKINMQTLLFPWPLPTVHQHAIDGSIPPHGRSTIL"
modelled from a9s.1.A template
Seq Identity: 93.94%
Coverage: 17-394
GMQE: 0.66
QMEANDisCo Global: 0.87 ± 0.05
P4c precursor (Cop-A26L); A28L; major component of IMV surface tubules; p4c.
note= "DNA topoisomerase type I (Cop-H6R); H6R; similar to Vaccinia virus strain Copenhagen H6R; DNA topoisomerase"
codon_start= 1
product= "MPXVgp096"
protein_id= "URG34871.1"
translation="MRALFYKDGKLFTDNNFLNPVSDDNPAYEVLQHVKIPTHLTDVVVYEQTWEEALTRLIFVGSDSKGRRQYFYGKMHIQNRNAKRDRIFVRVYNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFIRFGKMKYLKENETVGLLTLKNKHIEISPDEIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSVSPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMATTILEMVKDKNFLDVVSKTTFDEFLSIVVDHVKSSTDG"
modelled from 2h7g.1.C template
Seq Identity: 97.77%
Coverage: 1-312
GMQE: 0.93
QMEANDisCo Global: 0.85 ± 0.05
DNA topoisomerase type I (Cop-H6R); H6R; similar to Vaccinia virus strain Copenhagen H6R; DNA topoisomerase.
note= "A31L RNA polymerase subunit (RPO35) (Cop-A29L) RNA polymerase, 35 kDa subunit similar to Vaccinia virus strain Copenhagen A29L"
codon_start= 1
product= "MPXVgp141"
protein_id= "URK20579.1"
translation="MQHPREENSIVVELEPALATFIKQGFNNLVKWPLLNIGVVLYNTSTAVNEEWLTAVEHIPTMKIFYKHIHKILTREMGFLVYLKRSQSEHDNYITLYDFDYYIIDKDTNSVTMVDKPTELKETLLHVFQEYRLKSSQTIELIAFSSGTVINEDIVSKLTFLDVEVFNREYNNVKTIIDPDFVSRSPFIVISPMGKLTFFVEVYSWFDFKSCFKDIIDFLEGTLIANIHNHMIKVGDCDETVSSYNPESGMLFVNDLMTMNIVNFFGCNSRLESYHRFDMTKVDVELFIKALSDACKKILSASNRL"
modelled from 6ric.1.C template
Seq Identity: 97.70%
Coverage: 3-305
GMQE: 0.96
QMEANDisCo Global: 0.92 ± 0.05
Rpo35, RNA-polymerase, 35-kDa subunit. Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
